{"id":634,"date":"2016-12-14T15:06:37","date_gmt":"2016-12-14T15:06:37","guid":{"rendered":"http:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/?p=634"},"modified":"2022-04-13T13:59:11","modified_gmt":"2022-04-13T13:59:11","slug":"induce-study-wins-jewel-in-the-crown-presentation-at-the-college-of-podiatry-annual-conference-and-exhibition-in-glasgow","status":"publish","type":"post","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/induce-study-wins-jewel-in-the-crown-presentation-at-the-college-of-podiatry-annual-conference-and-exhibition-in-glasgow\/","title":{"rendered":"INDUCE Study Wins \u2018Jewel In The Crown\u2019 Presentation At The College Of Podiatry Annual Conference And Exhibition In Glasgow"},"content":{"rendered":"<p><em>I presented at The College of Podiatry annual conference and exhibition in Glasgow on the 17th Nov 2016.\u00a0<a href=\"http:\/\/www.cardiff.ac.uk\/centre-for-trials-research\/research\/themes\/infections\/induce-study\" target=\"_blank\" rel=\"noopener\">The INDUCE study<\/a> was selected as the Jewel in the Crown presentation from around 50 entries of short papers and poster presentations. Following a prize giving I was able to present, on the main stage, an overview of the study background, its methods, results and conclusions. &#8211; Angela Jones<\/em><\/p>\n<h2>Getting involved in research<\/h2>\n<p>This was a fantastic opportunity for a clinician to become involved in research and to be able to take the study and the results to the professional society.\u00a0 I was warmly welcomed by eminent world class speakers to the stage and the presentation was very well received.\u00a0 The experience left me with a great sense of value for\u00a0the effort and achievements of all who took part in the study.<\/p>\n<h2>Objective<\/h2>\n<p>The lifetime risk of developing a diabetic foot ulcer (DFU) approaches 25% in the UK, resulting in direct costs for the care of DFUs at more than \u00a3250 million. Diagnosis of DFU infection remains entirely clinical with no objective test at the point of patient care to assist the clinician in antibiotic prescribing decisions.\u00a0\u00a0 The objective of this study is to establish the use of a point-of-care-test (POCT) to assist antibiotic prescribing decisions for diabetic foot ulcer infections.<\/p>\n<h2>Method<\/h2>\n<p>This is a pilot feasibility study which, opportunistically recruited patients from podiatry diabetic foot wound clinics.\u00a0 The study recruited 67 voluntary patients with diabetic foot wounds (44 non-infected, 21 mildly infected, 2 withdrawn).\u00a0 The study will compare clinical observations of the wound (gold standard) to the POCT results for C reactive protein (CRP), procalcitonin and calprotectin biological markers.<\/p>\n<h2>Objectives<\/h2>\n<p>The study objectives are threefold: To inform the feasibility of a subsequent randomised control trial, particularly in terms of trial recruitment and use of the POCTs.\u00a0 To determine the cut-off points for optimal negative predictive value (NPV) and positive predictive value (PPV) of a combination of the POCTs using a robust gold standard for ulcer infection. This would give proof of principle that a composite POCT can be safely used to inform the decision about infection\/no infection at initial assessment in a community setting.\u00a0 To develop an online educational tool for DFU infection and obtain feedback regarding its effectiveness from experienced clinicians and patients.<\/p>\n<h2>Conclusion<\/h2>\n<p>As results are yet to be analysed conclusions are pending for the first 2 objectives.\u00a0 The development of the online educational tool is nearing completion with favourable feedback being received from user groups.\u00a0 A focus group of podiatrists involved in the data collection has been instrumental in informing the feasibility of a future randomised control trial.<\/p>\n<h2>Find Out More About The INDUCE Study<\/h2>\n<p>Please visit the <a href=\"http:\/\/www.cardiff.ac.uk\/centre-for-trials-research\/research\/themes\/infections\/induce-study\" target=\"_blank\" rel=\"noopener\">Centre for Trials Research website<\/a>.<\/p>\n<h2>Key Facts<\/h2>\n<p>Chief Investigator: <a href=\"http:\/\/www.cardiff.ac.uk\/people\/view\/126419-ingram-john\" target=\"_blank\" rel=\"noopener\">Dr John Ingram<\/a><\/p>\n<p>Funder:\u00a0<a href=\"https:\/\/www.healthandcareresearch.gov.wales\" target=\"_blank\" rel=\"noopener\">Health Care Research Wales<\/a> (RfppB \u20131018)<\/p>\n<p>Sponsor: <a href=\"http:\/\/www.cardiffandvaleuhb.wales.nhs.uk\" target=\"_blank\" rel=\"noopener\">Cardiff and Vale University Health Board<\/a><\/p>\n<p>Study Coordinated by\u00a0the <a href=\"http:\/\/www.cardiff.ac.uk\/centre-for-trials-research\" target=\"_blank\" rel=\"noopener\">Centre for Trials Research<\/a><\/p>\n<p>&#8211; Blog contributed by Angela Jones,<\/p>\n<p>Specialist Podiatrist Cardiff &amp; Vale University Health Board | Podiatry<\/p>\n","protected":false},"excerpt":{"rendered":"I presented at The College of Podiatry annual conference and exhibition in Glasgow on the 17th Nov 2016.\u00a0The INDUCE study was selected as the Jewel in the Crown presentation from [&hellip;]","protected":false},"author":549,"featured_media":635,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[35],"tags":[53,10],"class_list":["post-634","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-infections","tag-infections","tag-south-east-wales-trials-unit"],"jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p7dIou-ae","jetpack-related-posts":[{"id":2252,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/domino-hd-team-at-jpnd-jpco-fund2-symposium\/","url_meta":{"origin":634,"position":0},"title":"DOMINO-HD Team At JPND \/JPco-fuND2 Symposium","author":"Monica Busse-Morris","date":"May 10, 2022","format":false,"excerpt":"The DOMINO-HD team attended the JPND \/JPco-fuND2 Symposium on Thursday 28 April 2022 at the Royal Museums of Fine Arts of Belgium in Brussels. This was an event designed to bring together consortia coordinators and early career investigators working on projects funded in the 2018 Health and Social Care JPND\u2026","rel":"","context":"In &quot;Events&quot;","block_context":{"text":"Events","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/events\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/05\/Monica-and-DOMINO-HD.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/05\/Monica-and-DOMINO-HD.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/05\/Monica-and-DOMINO-HD.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/05\/Monica-and-DOMINO-HD.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/05\/Monica-and-DOMINO-HD.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/05\/Monica-and-DOMINO-HD.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":553,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/uk-society-for-behavioural-medicine-uksbm-12th-annual-conference-in-cardiff\/","url_meta":{"origin":634,"position":1},"title":"UK Society for Behavioural Medicine (UKSBM): 12th Annual Conference in Cardiff","author":"Mark Kelson","date":"December 14, 2016","format":false,"excerpt":"The 12th UKSBM conference, organised by a team from the South East Wales Trials Unit (SEWTU) based in the Centre for Trials Research at Cardiff University, lead by Dr Rachel McNamara, was a resounding success. The theme chosen for the conference was \u201cComplex interventions in a complex world\u201d reflecting our\u2026","rel":"","context":"In &quot;Behaviour Change&quot;","block_context":{"text":"Behaviour Change","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/behaviour-change\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/BLS3114.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/BLS3114.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/BLS3114.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/BLS3114.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/BLS3114.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":1160,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/prep-fellowship-and-beyond\/","url_meta":{"origin":634,"position":2},"title":"My Fellowship, PrEP And Beyond","author":"David Gillespie","date":"October 2, 2018","format":false,"excerpt":"Dr David Gillespie is Deputy Director of the Infections, Inflammation and Immunity Division in the Centre for Trials Research - and starts a Health and Care Research Wales Funded Post-Doctoral Fellowship this week. He talks about his background, motivation and ambitions for the future - as well as why he\u2026","rel":"","context":"In &quot;Infections&quot;","block_context":{"text":"Infections","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/infections\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/07\/BLS8232.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/07\/BLS8232.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/07\/BLS8232.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/07\/BLS8232.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/07\/BLS8232.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":2089,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/vim-abstract-at-asco-2021\/","url_meta":{"origin":634,"position":3},"title":"VIM Abstract At ASCO 2021","author":"Richard Haggerty","date":"June 7, 2021","format":false,"excerpt":"Professor Dean Fennell\u00a0(Chief Investigator for VIM) presented results of the ground-breaking, investigator-led trial at the ASCO global conference on Sunday 6th June 2021. Centre for Trials Research are supporting VIM. The prestigious ASCO accepted an abstract of the primary results data submitted earlier this year. ASCO ASCO is the American\u2026","rel":"","context":"In &quot;Events&quot;","block_context":{"text":"Events","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/events\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2021\/06\/ASCO.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2021\/06\/ASCO.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2021\/06\/ASCO.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2021\/06\/ASCO.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2021\/06\/ASCO.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2021\/06\/ASCO.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":61,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/south-west-society-for-academic-primary-care-2016-annual-meeting\/","url_meta":{"origin":634,"position":4},"title":"South West Society for Academic Primary Care 2016 Annual Meeting","author":"Richard Haggerty","date":"March 23, 2016","format":false,"excerpt":"The South East Wales Trials Unit (SEWTU) based in the Centre for Trials Research at Cardiff University recently co-hosted the South West Society for Academic Primary Care 2016 Annual Meeting along with colleagues in the Division of Population Medicine. The event brought\u00a0together over 160 experts and researchers in the field\u2026","rel":"","context":"In &quot;Children and Young People&quot;","block_context":{"text":"Children and Young People","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/children-and-young-people\/"},"img":{"alt_text":"Gwenllian Moody presenting on the challenge of collecting focus group data in partnership with geographically dispersed and time-pressed professionals.","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/03\/SWSAPC-Gwen-scaled.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/03\/SWSAPC-Gwen-scaled.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/03\/SWSAPC-Gwen-scaled.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/03\/SWSAPC-Gwen-scaled.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/03\/SWSAPC-Gwen-scaled.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/03\/SWSAPC-Gwen-scaled.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2396,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/centre-for-trials-research-at-ictmc2022-6th-international-clinical-trials-methodology-conference-ictmc\/","url_meta":{"origin":634,"position":5},"title":"Centre for Trials Research At #ICTMC2022: 6th International Clinical Trials Methodology Conference (ICTMC)","author":"Cheney Drew","date":"October 27, 2022","format":false,"excerpt":"After a Covid related hiatus, so a year later than planned, the bi-annual International Clinical Trials Methodology Conference (ICTMC) was held in the beautiful spa town of Harrogate at the beginning of October 2022. The ICTMC meeting is a great opportunity to learn about all things methodological in the clinical\u2026","rel":"","context":"In &quot;Events&quot;","block_context":{"text":"Events","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/events\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/10\/ICTMC-2022.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/10\/ICTMC-2022.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/10\/ICTMC-2022.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/10\/ICTMC-2022.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/10\/ICTMC-2022.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2022\/10\/ICTMC-2022.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]}],"meta_box":[],"jetpack_featured_media_url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/348-Thurs-COPC16-scaled.jpeg","_links":{"self":[{"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/posts\/634","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/users\/549"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/comments?post=634"}],"version-history":[{"count":7,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/posts\/634\/revisions"}],"predecessor-version":[{"id":2239,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/posts\/634\/revisions\/2239"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/media\/635"}],"wp:attachment":[{"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/media?parent=634"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/categories?post=634"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/tags?post=634"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}