{"id":2089,"date":"2021-06-07T12:42:29","date_gmt":"2021-06-07T12:42:29","guid":{"rendered":"http:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/?p=2089"},"modified":"2022-04-13T13:59:09","modified_gmt":"2022-04-13T13:59:09","slug":"vim-abstract-at-asco-2021","status":"publish","type":"post","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/vim-abstract-at-asco-2021\/","title":{"rendered":"VIM Abstract At ASCO 2021"},"content":{"rendered":"\n

Professor Dean Fennell\u00a0(Chief Investigator for VIM) presented results of the ground-breaking, investigator-led trial at the ASCO global conference on Sunday 6th June 2021. Centre for Trials Research are supporting VIM. The prestigious ASCO accepted an abstract of the primary results<\/em> data submitted earlier this year.<\/em><\/p>\n\n\n\n

ASCO<\/h2>\n\n\n\n

ASCO is the American Society of Clinical Oncology is the world’s leading professional organisation for physicians and oncology professionals caring for people with cancer. The ASCO annual conference is the most prestigious conference in oncology.\u00a0The audience is oncologists and oncology researchers.<\/p>\n\n\n\n

Background to VIM<\/h2>\n\n\n\n

VIM is a randomised phase 2 trial comparing active supportive care plus an oral drug called vinorelbine with active supportive care alone in patients with malignant pleural mesothelioma of the lung who have progressed after receiving initial chemotherapy treatment.\u00a0The trial has completed recruitment and follow up and we have just completed the main analysis.\u00a0<\/p>\n\n\n\n

Study question VIM is answering<\/h2>\n\n\n\n

The trial aimed to show whether patients in the vinorelbine arm had a longer time until their disease progressed again, compared to those receiving active supportive care only. We found that the patients benefitted from receiving vinorelbine, these patients had an average of 4.2 months until disease progression, compared to an average 2.8 months with active supportive care alone.<\/p>\n\n\n\n

VIM study team<\/h2>\n\n\n\n

The Chief Investigator, Professor Dean Fennel, is based at the University of Leicester and is world renowned for his research into mesothelioma, and current president of the International Mesothelioma interest group. The study is lead at the Centre for Trials Research by Angela Casbard, with trial management team of Lisette Nixon and Georgina Gardner, and with Catharine Porter leading on the statistical analysis. Terri Kitson from the Centre is data manager for the study.<\/p>\n\n\n\n

Next steps for the study<\/h2>\n\n\n\n

We are currently drafting the trial publication which we hope to have ready for submission in a few weeks.<\/p>\n","protected":false},"excerpt":{"rendered":"Professor Dean Fennell\u00a0(Chief Investigator for VIM) presented results of the ground-breaking, investigator-led trial at the ASCO global conference on Sunday 6th June 2021. Centre for Trials Research are supporting VIM. […]","protected":false},"author":549,"featured_media":2090,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[7],"tags":[103,4],"class_list":["post-2089","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-events","tag-asco","tag-cancer-study"],"jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p7dIou-xH","jetpack-related-posts":[{"id":1676,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/my-asco-centre-for-trials-research-at-the-american-society-of-clinical-oncology-2019\/","url_meta":{"origin":2089,"position":0},"title":"My ASCO: Centre for Trials Research at the American Society of Clinical Oncology 2019","author":"Margherita Carucci","date":"July 25, 2019","format":false,"excerpt":"Background This year I\u2019ve had the great opportunity to attend ASCO (American Society of Clinical Oncology) conference as a Centre for Trials Research representative together with Professor Richard Adams, Director Cancer Division, and Catrin Cox for the presentation of the FAKTION study by the Chief Investigators (CIs), Dr Sacha Howell\u2026","rel":"","context":"In "Cancer Trial"","block_context":{"text":"Cancer Trial","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/cancer-trial\/"},"img":{"alt_text":"Centre for Trials Research at ASCO","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2019\/07\/IMG-20190604-WA0002.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2019\/07\/IMG-20190604-WA0002.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2019\/07\/IMG-20190604-WA0002.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2019\/07\/IMG-20190604-WA0002.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2019\/07\/IMG-20190604-WA0002.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2019\/07\/IMG-20190604-WA0002.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2734,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/faktion-and-the-breast-cancer-drug-paving-a-future-for-hormonal-therapies\/","url_meta":{"origin":2089,"position":1},"title":"FAKTION And The Breast Cancer Drug Paving A Future For Hormonal Therapies","author":"Margherita Carucci","date":"November 29, 2023","format":false,"excerpt":"- by Margherita Carucci and Angela Casbard on behalf of the FAKTION CTR Team When a patient is diagnosed with cancer, their doctor will prescribe a drug or a combination of drugs for destroying or keeping the cancer cells under control. But how do doctors know which drugs are the\u2026","rel":"","context":"In "Events"","block_context":{"text":"Events","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/events\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2023\/11\/Breast-Cancer-Breakthrough-The-FAKTION-Trials-Pioneering-Findings-at-ASCO.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2023\/11\/Breast-Cancer-Breakthrough-The-FAKTION-Trials-Pioneering-Findings-at-ASCO.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2023\/11\/Breast-Cancer-Breakthrough-The-FAKTION-Trials-Pioneering-Findings-at-ASCO.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2023\/11\/Breast-Cancer-Breakthrough-The-FAKTION-Trials-Pioneering-Findings-at-ASCO.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2023\/11\/Breast-Cancer-Breakthrough-The-FAKTION-Trials-Pioneering-Findings-at-ASCO.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2023\/11\/Breast-Cancer-Breakthrough-The-FAKTION-Trials-Pioneering-Findings-at-ASCO.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":14,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/fragmatic\/","url_meta":{"origin":2089,"position":2},"title":"FRAGMATIC: Results of the Largest UK Trial of Lung Cancer Patients with Low Molecular Weight Heparin","author":"Richard Haggerty","date":"February 9, 2016","format":false,"excerpt":"The results of the Fragmatic trial were recently published in the Journal of Clinical Oncology. The trial was funded by Cancer Research UK with support from Pfizer to answer this question: \u2018Should all newly diagnosed people with lung cancer be offered daily injections of a drug called dalteparin for six\u2026","rel":"","context":"In "Cancer Trial"","block_context":{"text":"Cancer Trial","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/cancer-trial\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/02\/030914_7609-scaled.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/02\/030914_7609-scaled.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/02\/030914_7609-scaled.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/02\/030914_7609-scaled.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/02\/030914_7609-scaled.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/02\/030914_7609-scaled.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2816,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/ovarian-cancer-awareness-month-and-valtive1\/","url_meta":{"origin":2089,"position":3},"title":"Ovarian Cancer Awareness Month And VALTIVE1","author":"Margherita Carucci","date":"March 1, 2024","format":false,"excerpt":"Ovarian cancer awareness month March is Ovarian Cancer Awareness Month. In this global campaign aiming at raising awareness, promoting research, fundraising, and supporting women with ovarian cancer around the world, we would like to introduce you to the VALTIVE1 study, one of the ovarian cancer trials that the Centre for\u2026","rel":"","context":"In "Events"","block_context":{"text":"Events","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/events\/"},"img":{"alt_text":"Image of Ovarian Cancer Month logo.","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2024\/03\/oca-2455641215.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2024\/03\/oca-2455641215.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2024\/03\/oca-2455641215.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2024\/03\/oca-2455641215.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":634,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/induce-study-wins-jewel-in-the-crown-presentation-at-the-college-of-podiatry-annual-conference-and-exhibition-in-glasgow\/","url_meta":{"origin":2089,"position":4},"title":"INDUCE Study Wins \u2018Jewel In The Crown\u2019 Presentation At The College Of Podiatry Annual Conference And Exhibition In Glasgow","author":"Richard Haggerty","date":"December 14, 2016","format":false,"excerpt":"I presented at The College of Podiatry annual conference and exhibition in Glasgow on the 17th Nov 2016.\u00a0The INDUCE study was selected as the Jewel in the Crown presentation from around 50 entries of short papers and poster presentations. Following a prize giving I was able to present, on the\u2026","rel":"","context":"In "Infections"","block_context":{"text":"Infections","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/infections\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/348-Thurs-COPC16-scaled.jpeg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/348-Thurs-COPC16-scaled.jpeg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/348-Thurs-COPC16-scaled.jpeg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/348-Thurs-COPC16-scaled.jpeg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/348-Thurs-COPC16-scaled.jpeg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2016\/12\/348-Thurs-COPC16-scaled.jpeg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2597,"url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/international-congress-of-the-european-haematology-association-conference-in-frankfurt-germany-june-2023\/","url_meta":{"origin":2089,"position":5},"title":"International Congress of the European Haematology Association Conference in Frankfurt Germany June 2023","author":"Richard Haggerty","date":"June 22, 2023","format":false,"excerpt":"International Congress of the European Haematology Association Conference in Frankfurt, Germany \u2013 8th-11th June 2023 With more than 12,000 delegates a year, this conference is the leading meeting place for haematologists in all fields of this speciality in Europe and beyond.\u00a0 The focus for the CTR attendees, (myself, Joanna Canham\u2026","rel":"","context":"In "Events"","block_context":{"text":"Events","link":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/category\/events\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"meta_box":[],"jetpack_featured_media_url":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-content\/uploads\/sites\/499\/2021\/06\/ASCO.jpg","_links":{"self":[{"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/posts\/2089","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/users\/549"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/comments?post=2089"}],"version-history":[{"count":4,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/posts\/2089\/revisions"}],"predecessor-version":[{"id":2097,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/posts\/2089\/revisions\/2097"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/media\/2090"}],"wp:attachment":[{"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/media?parent=2089"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/categories?post=2089"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.cardiff.ac.uk\/centre-for-trials-research\/wp-json\/wp\/v2\/tags?post=2089"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}