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Enzyme MechanismsSynthetic Biology

Cofactor Recycling Paper Published

9 January 2017

Congratulations to Antonio, Will and Louis whose new paper in ACS Catalysis has been chosen to be highlighted as an Editor's Choice in Chemical & Engineering News.

Antonio has created a glutathione-based system for NADP+ regeneration. This is important because cofactors can be extremely expensive, limiting the use of enzymes that require them for synthesis. However, Antonio's novel system results in a high cofactor turnover number that can reduce the cost of NADP+-dependent biocatalytic processes up to 500,000-fold. Read more here (Open Access).