Not Your Grandfather’s Chemistry

Posted on 5th February 2017 by

A robust response to a frequent complaint: In recent years, the awards of Nobel Prize in Chemistry has generated discontent among some chemists who complain that more and more the Chemistry Prize is given to biologists, with expressions like "But, is this chemistry?" With all due respect to "chemist" colleagues who ask the question, or
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Flow Enzymology

Posted on 20th January 2017 by

In a new paper in the European Journal of Organic Chemistry, Xiaoping shows how the yield of terpene cyclase reactions can be dramatically improved using a flow reactor. In cases where release of a hydrophobic product is rate-limiting, intimate contact with an organic phase is essential to improve turnover, however rapid stirring can precipitate the
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New BBRSC Grant Awarded

Posted on 15th January 2017 by

The BBSRC has recently awarded a grant to a collaborative proposal between the Allemann, Luk and Tsai groups from the Cardiff University School of Chemistry and Prof. Arwyn Jones from the School of Pharmacy and Pharmaceutical Science. Together, we will create a specialised tool that allows us to introduce a protein of interest into cells
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Cofactor Recycling Paper Published

Posted on 9th January 2017 by

Congratulations to Antonio, Will and Louis whose new paper in ACS Catalysis has been chosen to be highlighted as an Editor's Choice in Chemical & Engineering News. Antonio has created a glutathione-based system for NADP+ regeneration. This is important because cofactors can be extremely expensive, limiting the use of enzymes that require them for synthesis.
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swbio

SWBio DTP PhD Positions Available

Posted on 9th November 2016 by

We are delighted to announce the availability of two South West Biosciences Doctoral Training Programme PhD positions: "Fungal Hosts for Production of Unusual and Unnatural Terpene Cyclase Feedstocks" and "Designing Terpene Synthase Specificity Through a Combined Computational and Synthetic Biology Approach". The first project aims to use synthetic biology approached to transfer enzymes that synthesise
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Antonio gives his talk at the 2016 Cardiff Chemistry Conference

Cardiff Chemistry Conference

Posted on 10th May 2016 by

The 15th annual Cardiff Chemistry Conference was held this week. The conference opened with a welcome and remarks from the Head of School of Chemistry, Prof. Allemann. After Prof. Holger Braunschweig opened the conference, the programme segued smoothly from Antonio's presentation on dihydrofolate biosynthesis into Prof. Sabine Flitsch's talk on enzyme cascades.
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